Physico-Morphological Characteristics of Aorta in Stroke-Prone and -Resistant Spontaneously Hypertensive Rats
نویسندگان
چکیده
منابع مشابه
Stroke-Prone Spontaneously Hypertensive Rats
Background and Purpose We examined metabolic and functional changes when forebrain ischemia was induced in strokeprone spontaneously hypertensive rats by bilateral carotid artery occlusion. In addition, the protective effect of clentiazem was evaluated in this model. Methods Rats were anesthetized with urethane. Cerebral blood flow was measured with a laser Doppler fkrwmeter. Cerebral high-ener...
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BACKGROUND AND PURPOSE In the spontaneously hypertensive stroke-prone rat, it is unclear whether plasminogen activator plays a role in the development of stroke. The present study was undertaken to investigate brain levels of plasminogen activator activity in spontaneously hypertensive stroke-prone rats and Wistar-Kyoto rats. METHODS Plasminogen activator was purified from the brains of rats ...
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Platelet survival was studied by using 51Cr-labeled platelets in stroke-prone spontaneously hypertensive rats (SHRSP), stroke-resistant SHR (SHRSR) and normotensive control rats of the Wistar-Kyoto (WK) strain. Relatively young animals of the same age prior to the development of cerebrovascular lesions (cerebral infarction and/or hemorrhage) were used. Platelet half-life time in SHRSP was sligh...
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Differences of alcohol drinking behavior, brain dopamine (DA) and serotonin (5-HT) levels and releases in the striatum were investigated in stroke-prone spontaneously hypertensive rats (SHRSP) and age-matched stroke-resistant spontaneously hypertensive rats (SHRSR). Voluntary alcohol (EtOH) consumption in SHRSP rats increased at 1 and 2 hours in the 4 hour time access. In the DA level, SHRSP sh...
متن کاملPhysical characteristics of the aortas in old stroke-prone spontaneously hypertensive rats.
In order to study the possible alteration of arterial walls in relation to the genetic desposition of stroke, the physical characteristics of the aortas in stroke-prone SHR (SHRSP) and Kyo: Wister (WK), which was the origin of SHR, were investigated previously and was reported that the aorta of SHRSP was more brittle than those of WK (Jap Heart J 16: 293, 1975). We modified the technique to det...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 1975
ISSN: 0021-4868,1348-673X
DOI: 10.1536/ihj.16.296